A unified framework for phylodynamic inference of epidemic spread
Event details
| Date | 19.07.2013 |
| Hour | 14:15 › 15:00 |
| Speaker | Dr. Tanja Stadler (ETHZ) |
| Location |
MA 1 12
|
| Category | Conferences - Seminars |
Epidemiological processes leave a fingerprint in the pattern of genetic structure of pathogen populations. I present a unified framework to infer these epidemiological processes directly from pathogen sequence data. The framework is based on phylogenetic analysis using common epidemiological models, such as SIR models. Our method is flexible as it allows for epidemic dynamics changing through time, or for heterogeneous host and pathogen populations. The method is intended as a powerful alternative to the commonly used coalescent skyline plot, as it overcomes the limitations of the coalescent approaches. Finally I discuss novel insights into the HIV-1 epidemic revealed by our method. The new methodology is available within the BEAST v2.0 software package.
Practical information
- General public
- Free
Organizer
- Prof. S. Morgenthaler