“Attenuating oncogenic transcription with small molecules”
Event details
| Date | 27.05.2021 |
| Hour | 16:00 › 17:30 |
| Speaker | Angela KOEHLER Goldblith Career Development Professor in Applied Biology, Department of Biological Engineering, MIT Koch Institute for Integrative Cancer Research, MIT, Institute Member, Board Institute of MIT and Harvard, MIT Center for Precision Cancer Medicine, Cambridge - USA |
| Location | Online |
| Category | Conferences - Seminars |
A Lola and John Grace Distinguished Lecture in Cancer Research
Angela received her B.A. in Biochemistry and Molecular Biology from Reed College in 1997. There she worked under the guidance of Professor Arthur Glasfeld on structural and biochemical studies of proteins that recognize tRNA or DNA. In 2003, she received her PhD in Chemistry from Harvard University where she worked with Professor Stuart Schreiber to develop novel technologies for identifying and characterizing interactions between proteins and small molecules. Upon graduation, she became an Institute Fellow in the Chemical Biology Program at the Broad Institute and a Group Leader for the NCI Initiative for Chemical Genetics. She is also a Project Leader in the NCI Cancer Target Discovery and Development (CTD2) Center at the Broad Institute aimed at targeting causal cancer genes with small molecules.
The Koehler lab is focused on building chemical tools and methods for studying temporal aspects of transcriptional regulation in development and disease with a focus on cancer. The lab pursues these goals by discovering and developing direct small-molecule probes of proteins involved in transcriptional regulation such as transcription factors and chromatin modifying enzymes.
Angela received her B.A. in Biochemistry and Molecular Biology from Reed College in 1997. There she worked under the guidance of Professor Arthur Glasfeld on structural and biochemical studies of proteins that recognize tRNA or DNA. In 2003, she received her PhD in Chemistry from Harvard University where she worked with Professor Stuart Schreiber to develop novel technologies for identifying and characterizing interactions between proteins and small molecules. Upon graduation, she became an Institute Fellow in the Chemical Biology Program at the Broad Institute and a Group Leader for the NCI Initiative for Chemical Genetics. She is also a Project Leader in the NCI Cancer Target Discovery and Development (CTD2) Center at the Broad Institute aimed at targeting causal cancer genes with small molecules.
The Koehler lab is focused on building chemical tools and methods for studying temporal aspects of transcriptional regulation in development and disease with a focus on cancer. The lab pursues these goals by discovering and developing direct small-molecule probes of proteins involved in transcriptional regulation such as transcription factors and chromatin modifying enzymes.
Practical information
- Informed public
- Free
Organizer
- Etienne MEYLAN
Contact
- Lisa Smith (please contact me for the Zoom passcode) - [email protected]