Biomimetic Natural Product Synthesis


Event details

Date 23.11.2021 17:1518:15  
Speaker Prof. Andrew Lawrence, University of Edinburgh, UK
Category Conferences - Seminars
Event Language English
Abstract: This presentation will be an account of our research into how molecular complexity is rapidly and selectively generated in biosynthetic pathways. We are focused on developing step-economical total syntheses that facilitate the production of practical quantities of our target molecules. This approach towards total synthesis enables greater collaborative research on the properties of these natural products whilst forcing us to tackle important reactivity and selectivity issues without resorting to the excessive use of non-strategic manipulations. By following a biomimetic approach we have developed several bio-inspired domino reaction sequences that rapidly and selectively generate molecular complexity (i.e., new bonds, rings and stereogenic elements). We are simultaneously, therefore, able to improve synthetic organic chemistry whilst probing fundamental questions regarding the chemistry of biosynthetic pathways.

Practical information

  • General public
  • Free