Elucidating the functions and mechanisms of inositol pyrophosphate messengers with chemical tools
Event details
| Date | 08.02.2016 |
| Hour | 16:15 › 18:00 |
| Speaker |
Prof. Dorothea Fiedler , Director at Leibniz-Institut für Molekulare Pharmakologie (FMP), Berlin, Germany. Bio: Dorothea grew up in the most beautiful city in Germany: Hamburg. She went to college at the University of Wuerzburg and did her Diploma work at UC Berkeley. She decided she liked the United States for many reasons that include Thanksgiving (and also German beers are overrated), so she stayed at Berkeley for her Ph.D. She worked in the Raymond and Bergman labs, studying host-guest systems and their application to catalysis. She then moved across the Bay to UCSF, where she joined the Shokat lab to investigate signal transduction pathways. She started her academic career at Princeton University but recently relocated to the FMP, Berlin. |
| Location | |
| Category | Conferences - Seminars |
Prof. Fiedler's group seeks to develop a better understanding of the multiple ways in which nature utilizes phosphate in both protein signaling cascades and metabolic networks. Specifically her research focuses on the following areas:
1) Signaling functions of inositol pyrophosphate messengers in metabolic disorders
2) The role of inorganic phosphate in cancer metabolism and metastasis
3) Activity based probes for profiling serine-threonine phosphatases in cancer progression
Common to all projects is a multi-disciplinary approach that combines techniques in inorganic and organic chemistry, chemical genetics and genetics, molecular biology and proteomics.
1) Signaling functions of inositol pyrophosphate messengers in metabolic disorders
2) The role of inorganic phosphate in cancer metabolism and metastasis
3) Activity based probes for profiling serine-threonine phosphatases in cancer progression
Common to all projects is a multi-disciplinary approach that combines techniques in inorganic and organic chemistry, chemical genetics and genetics, molecular biology and proteomics.
Practical information
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