EPFL BioE Talks SERIES "Enveloped Viruses and Coated Vesicles: New Insights From Cryo-Electron Microscopy"
Event details
| Date | 09.12.2024 |
| Hour | 12:15 › 13:15 |
| Speaker | Prof. John Briggs, Max Planck Institute of Biochemistry, Martinsried/Munich (DE) |
| Location | Online |
| Category | Conferences - Seminars |
| Event Language | English |
WEEKLY EPFL BIOE TALKS SERIES (sandwiches provided)
Abstract:
Cryo-electron microscopy, cryo-electron tomography and computational image processing can be combined to determine the structures of proteins within complex environments like cells and irregular viruses. We are applying these techniques to understand how proteins interact with one another and with lipids to assemble enveloped viruses and coated vesicles, and to understand how the proteins then rearrange to adapt their functions at different stages of the virus or vesicle lifecycle. I will illustrate recent work where we have determined structures of proteins to high-resolution in-situ, with a particular focus on the biology of HIV-1.
Bio:
Born in Great Britain. Study of Natural Sciences (Biochemistry), University of Cambridge, UK (1996 – 2000), doctorate in Structural Biology at University of Oxford, UK (2004), postdoctoral fellow at LMU, Munich (2005 – 2006), group leader at EMBL, Heidelberg (2006 – 2018), programme leader at MRC Laboratory of Molecular Biology, Cambridge, UK (2017 - 2021), director at Max Planck Institute of Biochemistry (since 2021).
Zoom link (with one-time registration for the whole series) for attending remotely: https://go.epfl.ch/EPFLBioETalks
Instructions for 1st-year Ph.D. students who are under EDBB’s mandatory seminar attendance rule:
IN CASE you cannot attend in-person in the room, please make sure to
Abstract:
Cryo-electron microscopy, cryo-electron tomography and computational image processing can be combined to determine the structures of proteins within complex environments like cells and irregular viruses. We are applying these techniques to understand how proteins interact with one another and with lipids to assemble enveloped viruses and coated vesicles, and to understand how the proteins then rearrange to adapt their functions at different stages of the virus or vesicle lifecycle. I will illustrate recent work where we have determined structures of proteins to high-resolution in-situ, with a particular focus on the biology of HIV-1.
Bio:
Born in Great Britain. Study of Natural Sciences (Biochemistry), University of Cambridge, UK (1996 – 2000), doctorate in Structural Biology at University of Oxford, UK (2004), postdoctoral fellow at LMU, Munich (2005 – 2006), group leader at EMBL, Heidelberg (2006 – 2018), programme leader at MRC Laboratory of Molecular Biology, Cambridge, UK (2017 - 2021), director at Max Planck Institute of Biochemistry (since 2021).
Zoom link (with one-time registration for the whole series) for attending remotely: https://go.epfl.ch/EPFLBioETalks
Instructions for 1st-year Ph.D. students who are under EDBB’s mandatory seminar attendance rule:
IN CASE you cannot attend in-person in the room, please make sure to
- send D. Reinhard a note well ahead of time (ideally before seminar day), informing that you plan to attend the talk online, and, during seminar:
- be signed in on Zoom with a recognizable user name (not any alias making it difficult or impossible to identify you).
Practical information
- Informed public
- Registration required
Organizer
- Prof. Henning Stahlberg, Institute of Bioengineering
Contact
- Institute of Bioengineering (IBI), Dietrich REINHARD