Extracellular small RNAs in host-bacteria interactions

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Event details

Date 07.10.2025
Hour 12:1513:15
Speaker Lionel Navarro, Institut de Biologie de l’École normale supérieure (IBENS), Paris
Location
Category Conferences - Seminars
Event Language English

Extracellular plant small RNAs (sRNAs) act as triggers of RNA interference (RNAi) in interacting fungal and oomycetal pathogens. However, whether these extracellular RNA species direct gene silencing in plant-associated bacteria, which are thought to lack a canonical eukaryotic-like RNAi machinery, remains elusive. Here, I will present recent findings from the team demonstrating the occurrence of a cross-kingdom RNAi phenomenon implicating the trafficking of sRNAs from plant cells towards bacterial cells. In particular, I will report on the vesicular and non-vesicular extracellular sRNAs that are causal for this gene regulatory process. Finally, I will touch upon approaches that are currently developed to translate these discoveries towards novel solutions to control bacterial infections in plants and mammals.

Practical information

  • Informed public
  • Free

Organizer

  • Bruno Lemaitre

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