Extracellular small RNAs in host-bacteria interactions

Event details
Date | 07.10.2025 |
Hour | 12:15 › 13:15 |
Speaker | Lionel Navarro, Institut de Biologie de l’École normale supérieure (IBENS), Paris |
Location | |
Category | Conferences - Seminars |
Event Language | English |
Extracellular plant small RNAs (sRNAs) act as triggers of RNA interference (RNAi) in interacting fungal and oomycetal pathogens. However, whether these extracellular RNA species direct gene silencing in plant-associated bacteria, which are thought to lack a canonical eukaryotic-like RNAi machinery, remains elusive. Here, I will present recent findings from the team demonstrating the occurrence of a cross-kingdom RNAi phenomenon implicating the trafficking of sRNAs from plant cells towards bacterial cells. In particular, I will report on the vesicular and non-vesicular extracellular sRNAs that are causal for this gene regulatory process. Finally, I will touch upon approaches that are currently developed to translate these discoveries towards novel solutions to control bacterial infections in plants and mammals.
Practical information
- Informed public
- Free
Organizer
- Bruno Lemaitre