“Inflammation and Immune response in the leukemia microenvironment”
A Lola and John Grace Distinguished Lecture in Cancer Research
Dr Iannis Aifantis, Hermann M. Biggs Professor and Chair
Department of Pathology, NYU School of Medicine, USA
Dr Aifantis's lab studies the molecular mechanisms driving normal stem cell differentiation and malignant transformation. More specifically, they are using the hematopoietic system as their model of study and focus on the genomic, epigenetic and proteomic regulation of hematopoietic stem cell differentiation and induction of leukemia and lymphoma. Their latest obsessions are diverse regulatory mechanisms including ubiquitin-regulated protein abundance, DNA and Histone methylation and the role of long non-coding RNAs in leukemia induction, progression and relapse after treatment. Finally, they are interested to visualize and measure the impact of tumor micro-environment on these regulatory mechanisms and test drugs that will target either the tumor or the tumor niche using both animal and human xenograft disease models.
Practical information
- Informed public
- Free
- This event is internal
Organizer
- Prof. Elisa Oricchio
Contact
- Lisa Smith, ISREC Administrative Assistant (merci de me contacter pour le mot de passe Zoom)