Intracellular activities of Salmonella
Event details
| Date | 16.09.2010 |
| Hour | 14:00 |
| Speaker | Prof. David Holden, Imperial College, London |
| Location |
SV 1717A
|
| Category | Conferences - Seminars |
Following entry of Salmonella into host cells, this pathogen remains in a membrane-bound compartment called the Salmonella-containing vacuole (SCV). Bacteria sense both the vacuolar and cyctosolic environments and activate the expression of the SPI-2 type III secretion system (T3SS), and translocation of its effectors. The SPI-2 T3SS has been implicated in several physiological activities, including avoidance of killing by macrophages, bacterial replication in a variety of host cell types, interference with immune signalling and the induction of cytotoxicity. I will describe recent progress in our laboratory on the functions of this complicated system.
Links
Practical information
- General public
- Free
Organizer
- Prof. Gisou van der Goot
Contact
- Prof. Gisou van der Goot