Pathogenesis of polymicrobial biofilm-associated infections

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Event details

Date 21.02.2023
Hour 12:1513:15
Speaker Kimberly Kline, Department of Microbiology and Molecular Medicine - Faculty of Medicine, University of Geneva
Location
Category Conferences - Seminars
Event Language English

The Gram-positive Enterococci are commensal inhabitants of the gastrointestinal tract, as well as opportunistic pathogens associated with endocarditis, urinary tract infections, and wound infection. Many Enterococcal infections are difficult to treat due to their multi-drug resistance, association with bacterial biofilms, and polymicrobial nature. The goal of our research is to understand the molecular mechanisms by which Enterococcus faecalis interacts with other bacterial species, such as Staphylococcus aureus and Escherichia coli, and the host in the context of these polymicrobial, biofilm-associated infections. In this talk, I will share our most recent mechanistic discoveries of synergy and antagonism between these frequently co-isolated bacterial species within the complex ecological environment of the host, and the impact of these interactions on biofilm-associated infection outcomes.

Practical information

  • Informed public
  • Free

Organizer

  • Alexandre Persat

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