The Integron adaptive system: a tale of bacterial ingenuity
Event details
| Date | 21.01.2025 |
| Hour | 12:15 › 13:15 |
| Speaker | Céline Loot, Bacterial Genome Plasticity lab, Department of Genomes and Genetics, Pasteur Institute |
| Location | |
| Category | Conferences - Seminars |
| Event Language | English |
Integrons are powerful genetic systems involved in bacterial evolution. They recruit genes embedded in cassettes, facilitating the acquisition of new functions. They also shuffle their array of gene cassettes, thereby modulating gene expression. This guarantees combinatorial phenotypic diversity, enabling bacteria to seek out the set of functions that will optimize their survival in a given environment. This process facilitates adaptation by avoiding time-consuming de novo evolutionary innovation. While the small mobile integrons carried by plasmids play a crucial role in the development of antibiotic resistance, their larger counterparts, located in chromosomes, act as reservoirs of adaptive functions. I will present our recent work highlighting the dissemination mechanism of cassettes as well as the functions associated with them.
Practical information
- Informed public
- Free
Organizer
- Melanie Blokesch