Events
retrieve:
Return the details about the given Memento id.
list:
List all Memento objects.
GET /api/v1/mementos/111/events/?format=api
{ "count": 11, "next": "https://memento.epfl.ch/api/v1/mementos/111/events/?format=api&limit=10&offset=10", "previous": null, "results": [ { "id": 72194, "title": "Neuro-X seminar: Prof Tim O'Shea - Engineering astrocytes to promote wound repair and modulate foreign body responses in the CNS", "slug": "neuro-x-seminar-prof-tim-o-shea-engineering-astroc", "event_url": "https://memento.epfl.ch/event/neuro-x-seminar-prof-tim-o-shea-engineering-astroc", "visual_url": "https://memento.epfl.ch/image/33474/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33474/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33474/max-size.jpg", "lang": "en", "start_date": "2026-10-09", "end_date": "2026-10-09", "start_time": "11:00:00", "end_time": "12:00:00", "description": "<p>Astrocytes are the predominant glial cells in the mammalian central nervous system (CNS) and play essential roles in maintaining neural circuit activity and tissue homeostasis. In response to CNS insult, including traumatic injury or implantation of a medical device, astrocytes undergo a conserved, temporally regulated reprogramming that reshapes their prioritized functions to protect adjacent neural tissue. The nature and extent of astrocyte reprogramming critically influences outcomes after CNS insult. For example, regeneration after traumatic CNS injury in adult mammals is limited by local responding astrocytes lacking sufficient self-renewal capacity. By contrast, the CNS of neonate (newborn) mammals possesses exceptional parenchymal repair capacity owing to immature astrocytes with elevated proliferative and migratory potential. In the context of an implanted medical device, the spatial extent of astrocyte reprogramming and how impacted astrocytes respond to any further device micromotion, latent infection, or other persistent device-derived stimuli, dictates device performance and longevity. Engineering astrocyte responses to promote targeted functional gains while preserving key capabilities of healthy neural tissue astrocytes will be critical to enabling effective neural regeneration therapies and improving long-term performance of implanted devices. In this talk, I will outline our emerging understanding of how adult astrocytes adaptively reprogram in response to CNS injury and implanted foreign bodies, drawing insights from innovative astrocyte-specific transcriptomic bioassays. I will also provide an overview of biomaterial and cell-grafting strategies that we are exploring to direct astrocyte responses in preclinical models of stroke, spinal cord injury, and foreign body responses.<br>\r\n<br>\r\n<strong>Bio:</strong><br>\r\n<strong>Dr. Timothy O’Shea, PhD</strong> is an Assistant Professor in the Biomedical Engineering department at Boston University (BU). Tim grew up in Brisbane, Australia and completed a Bachelor of Medical Engineering (First Class Honours) and a Masters in Engineering Management at Queensland University of Technology (QUT) before moving to the US for graduate school. He completed his PhD study in Medical Engineering and Medical Physics within the collaborative Health Sciences and Technology program of the Harvard Medical School and the Massachusetts Institute of Technology where we conducted PhD thesis research with Institute Professor Robert Langer. As a Postdoctoral Fellow in Neurobiology at UCLA, he worked with Professors Michael Sofroniew (Neurobiology) and Timothy Deming (Bioengineering) developing and testing novel bioengineering tools to study biological mechanisms involved in CNS injury and repair as well as the CNS foreign body response to implants. Since Fall 2020 he has been leading the Glia Engineering Lab at BU where he has received numerous awards including the Maximizing Investigators' Research Award (MIRA) from NIH and grants from several spinal cord injury research foundations such as Craig H Neilsen, Paralyzed Veterans of America, Bryon Reisch, and Wings for Life.</p>", "image_description": "", "creation_date": "2026-07-01T12:06:17", "last_modification_date": "2026-09-29T15:26:49", "link_label": "", "link_url": "", "canceled": "False", "cancel_reason": "", "place_and_room": "B1-6", "url_place_and_room": "https://plan.epfl.ch/?room==B1%206%20272.043", "url_online_room": "https://epfl.zoom.us/j/62394730036?pwd=jz0K4NPrEtbqswaGBRIOJ0Kf64PwYm.1", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "<a href=\"https://www.bu.edu/eng/profile/timothy-oshea-ph-d/\">Tim O'Shea</a>", "organizer": "<a href=\"http://people.epfl.ch/mark.anderson\">Mark Anderson</a>", "contact": "<a href=\"https://people.epfl.ch/niels.lion?lang=en\">Niels Lion</a>", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/121206/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/19/?format=api", "https://memento.epfl.ch/api/v1/mementos/111/?format=api", "https://memento.epfl.ch/api/v1/mementos/392/?format=api" ] }, { "id": 72640, "title": "EPFL BioEngineering Talks", "slug": "epfl-bioengineering-talks-11", "event_url": "https://memento.epfl.ch/event/epfl-bioengineering-talks-11", "visual_url": "https://memento.epfl.ch/image/33885/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33885/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33885/max-size.jpg", "lang": "en", "start_date": "2026-10-12", "end_date": "2026-10-12", "start_time": "12:15:00", "end_time": "13:00:00", "description": "<p>Weekly BioEngineering Talks (Lunch Provided)<br>\r\n<br>\r\n<strong>INVITED SPEAKER:</strong><br>\r\n<br>\r\n<strong>De novo design of light-responsive proteins</strong><br>\r\n<a href=\"https://people.epfl.ch/alexander.hilditch?lang=en\"><strong>Dr. Alexander Hilditch</strong>,</a> EPFL Laboratory of Protein Design & Immunoengineering <br>\r\nHost: <a href=\"https://people.epfl.ch/bruno.correia?lang=en\">Prof. Bruno Correia</a><br>\r\n<br>\r\n<br>\r\n------------------------------------------------------------------------------<br>\r\n<br>\r\n<strong>BioEngineering Talks mandatory EDBB Seminar Attendance (1st-Year PhD Students)</strong>\r\n</p><ul>\r\n\t<li> Attendance sheet to print <a class=\"text-link\" href=\"https://docs.google.com/document/d/1kusGxCFPAvWaRD8eUGEBkSVzD1ppMf1g/edit\" target=\"_blank\">HERE </a></li>\r\n</ul>\r\n<strong>The BioEngineering Student Seminar Series</strong> is an official course for which students can register and earn credits.<br>\r\n \r\n<ul>\r\n\t<li>Register <a class=\"text-link\" href=\"https://edu.epfl.ch/studyplan/fr/ecole_doctorale/biotechnologie-et-genie-biologique/coursebook/bioengineering-student-seminar-series-BIOENG-613\" target=\"_blank\">HERE</a></li>\r\n\t<li>Attendance sheet to print <a class=\"text-link\" href=\"https://docs.google.com/document/d/1ZGrPnt8LlLuWOApzx32s6L5UPPH8Hyoo/edit\" target=\"_blank\">HERE</a></li>\r\n</ul>\r\n<strong>General information:</strong><br>\r\nIn-person attendance is preferred to support your fellow students. Zoom is mainly for students on remote campuses; please notify <a class=\"text-link\" href=\"mailto:[email protected]\" target=\"_blank\">Fiorella Ghisays</a> in advance and join using your full name.<br>\r\nIf attending in person, have your sheet signed after the talk and keep the original, as no copy is retained.<br>\r\n ", "image_description": "", "creation_date": "2026-09-22T15:48:04", "last_modification_date": "2026-09-29T15:50:23", "link_label": "", "link_url": "", "canceled": "False", "cancel_reason": "", "place_and_room": "SV 1717", "url_place_and_room": "https://plan.epfl.ch/?room==SV%201717", "url_online_room": "https://epfl.zoom.us/j/68746410793", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "Invited Speaker and Student Speaker", "organizer": "Institute of Bioengineering", "contact": "<a href=\"mailto:[email protected]?subject=EPFL%20BioE%20Talks%20Series\">Fiorella Ghisays</a>, Institute of Bioengineering", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "", "file": "https://memento.epfl.ch/public/upload/files/BioEngineeringTalkMemento_u0lzmcg.jpg", "icalendar_url": "https://memento.epfl.ch/event/export/121882/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/1/?format=api", "https://memento.epfl.ch/api/v1/mementos/5/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api", "https://memento.epfl.ch/api/v1/mementos/8/?format=api", "https://memento.epfl.ch/api/v1/mementos/9/?format=api", "https://memento.epfl.ch/api/v1/mementos/111/?format=api", "https://memento.epfl.ch/api/v1/mementos/434/?format=api" ] }, { "id": 72373, "title": "Lysosomes at the nexus of cellular quality control and metabolism", "slug": "lysosomes-at-the-nexus-of-cellular-quality-control", "event_url": "https://memento.epfl.ch/event/lysosomes-at-the-nexus-of-cellular-quality-control", "visual_url": "https://memento.epfl.ch/image/33629/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33629/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33629/max-size.jpg", "lang": "en", "start_date": "2026-10-15", "end_date": "2026-10-15", "start_time": "16:00:00", "end_time": "17:00:00", "description": "<p>Lysosomes sit at the crossroads of cellular catabolism and quality control, where they must dismantle chemically diverse cargo while preserving their own integrity. I will discuss two discoveries that reveal how lysosomes solve these complementary challenges and how their failure creates disease vulnerabilities. First, I will describe Lysosomal Leucine Aminopeptidase (LyLAP), an enzyme specialized to processively degrade the hydrophobic α-helices of transmembrane proteins. LyLAP is highly expressed in pancreatic ductal adenocarcinoma, where its loss causes hydrophobic peptides to accumulate, compromises lysosomal function, and ultimately leads to cancer cell death, revealing a potential vulnerability in tumors with elevated endocytic activity. I will then describe LASER, a damage-responsive protein assembly that couples lysosomal membrane injury to repair. At its core, the oligomeric protein TFG recognizes LC3/GABARAP proteins conjugated to damaged lysosomes and recruits the ESCRT machinery to restore membrane integrity. Neurodegenerative disease-associated mutations in TFG disrupt this process, linking defective lysosomal repair to human disease. Together, these findings reveal lysosomes as dynamic systems that coordinate cargo degradation with membrane surveillance and repair to maintain cellular homeostasis. <br>\r\n<br>\r\nMore about Dr. Aakriti Jain's lab at UTSW: <a href=\"https://aakritijainlab.com/\">https://aakritijainlab.com/</a></p>", "image_description": "Dr. Aakriti Jain", "creation_date": "2026-08-19T11:24:24", "last_modification_date": "2026-09-21T16:54:33", "link_label": "", "link_url": "", "canceled": "False", "cancel_reason": "", "place_and_room": "SV 1717", "url_place_and_room": "https://plan.epfl.ch/?room==SV%201717", "url_online_room": "https://epfl.zoom.us/j/7467019292", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "Dr. Aakriti Jain, UTSW", "organizer": "Dr. Juan Manuel García-Arcos", "contact": "Dr. Juan Manuel García-Arcos, [email protected]", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "ESCRT, Lysosomal repair, organelle dynamics, Lysosomal Leucine Aminopeptidase, transmembrane protein degradation", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/121477/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/9/?format=api", "https://memento.epfl.ch/api/v1/mementos/111/?format=api" ] }, { "id": 72369, "title": "Mechanical forces as long-range organizers of cellular physiology", "slug": "mechanical-forces-as-long-range-organizers-of-cell", "event_url": "https://memento.epfl.ch/event/mechanical-forces-as-long-range-organizers-of-cell", "visual_url": "https://memento.epfl.ch/image/33626/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33626/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33626/max-size.jpg", "lang": "en", "start_date": "2026-10-16", "end_date": "2026-10-16", "start_time": "16:00:00", "end_time": "16:45:00", "description": "<p>In migrating cells, the GTPase Rac organizes a protrusive front, whereas Rho organizes a contractile back, yet how these GTPases segregate remains unclear. We leverage optogenetics, mechanical perturbations, and modeling to reveal a mechanochemical long-range mutual activation between front and back polarity programs that complements their known local mutual inhibition. Rac-driven protrusions increase membrane tension, triggering mTORC2-dependent Rho activation at the opposite side of the cell. Conversely, Rho-mediated contractility induces cortical-flow regulation of phosphoinositide signaling, promoting distal Rac activation. Our findings demonstrate how the actin cortex and plasma membrane interact as an integrated mechanochemical system for long-range Rac-Rho patterning. Efficient migration also requires polarized organization of the cell interior, with organelle positioning increasingly recognized as a key determinant of cell movement. Yet how this organization is established remains unclear. Building on our mechanochemical framework, we now investigate how actin-generated forces position organelles during migration and how disruption of this intracellular organization contributes to disease.<br>\r\n<br>\r\nWebsite of the De Belly lab: <a href=\"https://cri.utsw.edu/faculty/henry-de-belly/\">https://cri.utsw.edu/faculty/henry-de-belly/</a><br>\r\n<br>\r\nThis is part of the Physics of Living Systems monthly symposium: <a href=\"https://pols.epfl.ch/physics-of-living-systems-seminars/monthly-symposium/\">https://pols.epfl.ch/physics-of-living-systems-seminars/monthly-symposium/</a></p>", "image_description": "Dr. Henry De Belly, UTSW", "creation_date": "2026-08-19T11:02:03", "last_modification_date": "2026-08-19T12:10:32", "link_label": "", "link_url": "", "canceled": "False", "cancel_reason": "", "place_and_room": "SV 1717", "url_place_and_room": "https://plan.epfl.ch/?room==SV%201717", "url_online_room": "https://epfl.zoom.us/j/7467019292", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "Dr. Henry De Belly, UTSW", "organizer": "Dr. Juan Manuel García-Arcos, EPFL", "contact": "Dr. Juan Manuel García-Arcos, [email protected]", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "Mechanobiology, cell signalling, cell migration, mTORC2, Rho GTPases, cellular organization", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/121471/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/9/?format=api", "https://memento.epfl.ch/api/v1/mementos/111/?format=api" ] }, { "id": 72462, "title": "EPFL BioEngineering Talks", "slug": "epfl-bioengineering-talks-4", "event_url": "https://memento.epfl.ch/event/epfl-bioengineering-talks-4", "visual_url": "https://memento.epfl.ch/image/33710/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33710/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33710/max-size.jpg", "lang": "en", "start_date": "2026-10-19", "end_date": "2026-10-19", "start_time": "12:15:00", "end_time": "13:15:00", "description": "<p>Weekly BioEngineering Talks (Lunch Provided)<br>\r\n<br>\r\n<strong>INVITED SPEAKERS:</strong><br>\r\n<br>\r\n<strong>Organic electrochemical transistors for enhanced potentiometric sensing of neurochemicals</strong><br>\r\n<strong><a href=\"https://people.epfl.ch/emily.schafer?lang=en\">Dr. Emily Schafer,</a> </strong>EPFL Laboratory of Chemical Nanotechnology<br>\r\nHost: <a href=\"https://people.epfl.ch/nako.nakatsuka\">Prof. Nako Nakatsuka</a><br>\r\n<br>\r\nFollowed by<br>\r\n<br>\r\n<strong>Data-driven protein engineering for sensing and biosynthesis of new-to-nature thioesters</strong><br>\r\n<a href=\"https://people.epfl.ch/sebastian.barthel?lang=en\"><strong>Dr. Sebastian Barthel</strong>,</a> EPFL Laboratory of Synthetic and Applied Microbiology <br>\r\nHost: <a href=\"https://people.epfl.ch/markus.jeschek\">Prof. Markus Jeschek</a><br>\r\n<br>\r\n------------------------------------------------------------------------------<br>\r\n<br>\r\n<strong>BioEngineering Talks mandatory EDBB Seminar Attendance (1st-Year PhD Students)</strong>\r\n</p><ul>\r\n\t<li> Attendance sheet to print <a class=\"text-link\" href=\"https://docs.google.com/document/d/1kusGxCFPAvWaRD8eUGEBkSVzD1ppMf1g/edit\" target=\"_blank\">HERE </a></li>\r\n</ul>\r\n<strong>The BioEngineering Student Seminar Series</strong> is an official course for which students can register and earn credits.<br>\r\n \r\n<ul>\r\n\t<li>Register <a class=\"text-link\" href=\"https://edu.epfl.ch/studyplan/fr/ecole_doctorale/biotechnologie-et-genie-biologique/coursebook/bioengineering-student-seminar-series-BIOENG-613\" target=\"_blank\">HERE</a></li>\r\n\t<li>Attendance sheet to print <a class=\"text-link\" href=\"https://docs.google.com/document/d/1ZGrPnt8LlLuWOApzx32s6L5UPPH8Hyoo/edit\" target=\"_blank\">HERE</a></li>\r\n</ul>\r\n<strong>General information:</strong><br>\r\nIn-person attendance is preferred to support your fellow students. Zoom is mainly for students on remote campuses; please notify <a class=\"text-link\" href=\"mailto:[email protected]\" target=\"_blank\">Fiorella Ghisays</a> in advance and join using your full name.<br>\r\nIf attending in person, have your sheet signed after the talk and keep the original, as no copy is retained.<br>\r\n ", "image_description": "", "creation_date": "2026-08-28T08:14:49", "last_modification_date": "2026-09-22T15:58:20", "link_label": "", "link_url": "", "canceled": "False", "cancel_reason": "", "place_and_room": "SV 1717", "url_place_and_room": "https://plan.epfl.ch/?room==SV%201717", "url_online_room": "https://epfl.zoom.us/j/68746410793", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "Invited Speaker and Student Speaker", "organizer": "Institute of Bioengineering", "contact": "<a href=\"mailto:[email protected]?subject=EPFL%20BioE%20Talks%20Series\">Fiorella Ghisays</a>, Institute of Bioengineering", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "", "file": "https://memento.epfl.ch/public/upload/files/BioEngineeringTalkMemento_u0lzmcg.jpg", "icalendar_url": "https://memento.epfl.ch/event/export/121616/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/1/?format=api", "https://memento.epfl.ch/api/v1/mementos/5/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api", "https://memento.epfl.ch/api/v1/mementos/8/?format=api", "https://memento.epfl.ch/api/v1/mementos/9/?format=api", "https://memento.epfl.ch/api/v1/mementos/111/?format=api", "https://memento.epfl.ch/api/v1/mementos/434/?format=api" ] }, { "id": 72637, "title": "EPFL BioEngineering Talks", "slug": "epfl-bioengineering-talks-8", "event_url": "https://memento.epfl.ch/event/epfl-bioengineering-talks-8", "visual_url": "https://memento.epfl.ch/image/33882/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33882/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33882/max-size.jpg", "lang": "en", "start_date": "2026-10-26", "end_date": "2026-10-26", "start_time": "12:15:00", "end_time": "13:45:00", "description": "<p>Weekly BioEngineering Talks (Lunch Provided)<br>\r\n<br>\r\n<strong>INVITED SPEAKER:</strong><br>\r\n<br>\r\n<strong>Advancing Multidimensional Single-Molecule localization microscopy: development and applications in nuclear organization</strong><br>\r\n<a href=\"http://institut-curie.org/person/bassam-hajj\"><strong>Dr. Bassam Hajj</strong></a>, Institut Curie, Paris<br>\r\nHost: <a href=\"https://people.epfl.ch/aleksandra.radenovic?lang=en\">Prof. Aleksandra Radenovic</a><br>\r\n<br>\r\n<u><strong>Abstract:</strong></u><br>\r\nSingle-molecule localization microscopy (SMLM) has revolutionized our understanding of biological processes by providing access to spatial scales beyond the diffraction limit of conventional optical microscopy. In the study of the cell nucleus, SMLM has offered unique insights into its organization and function at the nanoscale. Nuclear architecture is structured across multiple spatial scales in three dimensions and is highly dynamic. Understanding the mechanisms that govern nuclear organization therefore requires imaging approaches capable of capturing molecular dynamics across a broad range of spatial and temporal scales and in diverse biological contexts. Although SMLM can routinely achieve spatial resolutions in the tens-of-nanometers range, many biologically relevant structures and processes remain beyond its reach. For example, resolving the precise organization of DNA at the molecular scale remains challenging, as it would require a substantial improvement in spatial resolution over conventional SMLM, while also addressing the high density and degree of molecular compaction within the nucleus. <br>\r\nOver the years, we have developed complementary strategies to address these challenges by introducing additional dimensions and observables into SMLM measurements. In this presentation, I will first discuss our approaches to three-dimensional single-molecule imaging, including multifocus microscopy and volumetric light-sheet excitation, which enable fast and sensitive imaging over extended volumes and in complex biological samples such as cell colonies. While these approaches provide access to the three-dimensional and temporal dimensions required to investigate nuclear organization, spatial resolution alone is not always sufficient to distinguish molecular arrangements. We have therefore extended SMLM further by implementing polarization-resolved multifocus microscopy (PolMFM), which combines three-dimensional localization with information on molecular orientation.<br>\r\nI will illustrate how these multidimensional approaches can provide new insights into nuclear organization, with examples spanning different biological systems. In particular, I will present evidence for a long-range, crystal-like organization of DNA within the nuclei of mature sperm cells from crickets, demonstrating how multidimensional imaging can reveal structural features that remain inaccessible to conventional localization microscopy.<br>\r\nFinally, I will discuss the challenges and opportunities associated with visualizing, analyzing, and interactively exploring the multidimensional datasets generated by these approaches. Together, these developments illustrate how extending SMLM beyond conventional two-dimensional localization can provide new ways to interrogate the organization and dynamics of biological systems at the nanoscale.<br>\r\n<br>\r\n<br>\r\n<u><strong>Bio:</strong></u><br>\r\nBassam Hajj is a physicist and CNRS researcher at Institut Curie in Paris, where he is a member of the Physics of Cells and Cancer unit and co-leads the “Light-based Observation and Control of Cellular Organization” team. His research focuses on the development of advanced optical microscopy techniques, particularly single-molecule localization microscopy, 3D imaging, and multidimensional approaches for studying cellular organization at the nanoscale.<br>\r\nAfter completing his PhD at École Normale Supérieure de Cachan on electro-optical microscopy, Bassam joined Janelia Research Campus as a postdoctoral researcher, where he worked on multifocus microscopy for fast and sensitive single-molecule imaging. He subsequently returned to Institut Curie and joined the CNRS as a permanent researcher in 2016.<br>\r\nHis current research combines innovative microscopy, quantitative image analysis, and data visualization to investigate molecular organization and dynamics, with a particular focus on nuclear organization.<br>\r\n<br>\r\n<strong>STUDENT SPEAKER:</strong><br>\r\n<br>\r\n<strong>Transcription Factor Dose in Stem Cell Reprogramming: Insights from Single-Cell Multi-Omics</strong><br>\r\n<strong><a href=\"https://people.epfl.ch/angelika.gebhart?lang=en\">Angelika Gebhart</a>, </strong><a href=\"https://www.epfl.ch/labs/deplanckelab/\">Deplancke Lab</a><br>\r\n<br>\r\n<br>\r\n------------------------------------------------------------------------------<br>\r\n<br>\r\n<strong>BioEngineering Talks mandatory EDBB Seminar Attendance (1st-Year PhD Students)</strong>\r\n</p><ul>\r\n\t<li> Attendance sheet to print <a class=\"text-link\" href=\"https://docs.google.com/document/d/1kusGxCFPAvWaRD8eUGEBkSVzD1ppMf1g/edit\" target=\"_blank\">HERE </a></li>\r\n</ul>\r\n<strong>The BioEngineering Student Seminar Series</strong> is an official course for which students can register and earn credits.<br>\r\n \r\n<ul>\r\n\t<li>Register <a class=\"text-link\" href=\"https://edu.epfl.ch/studyplan/fr/ecole_doctorale/biotechnologie-et-genie-biologique/coursebook/bioengineering-student-seminar-series-BIOENG-613\" target=\"_blank\">HERE</a></li>\r\n\t<li>Attendance sheet to print <a class=\"text-link\" href=\"https://docs.google.com/document/d/1ZGrPnt8LlLuWOApzx32s6L5UPPH8Hyoo/edit\" target=\"_blank\">HERE</a></li>\r\n</ul>\r\n<strong>General information:</strong><br>\r\nIn-person attendance is preferred to support your fellow students. Zoom is mainly for students on remote campuses; please notify <a class=\"text-link\" href=\"mailto:[email protected]\" target=\"_blank\">Fiorella Ghisays</a> in advance and join using your full name.<br>\r\nIf attending in person, have your sheet signed after the talk and keep the original, as no copy is retained.<br>\r\n ", "image_description": "", "creation_date": "2026-09-22T14:23:42", "last_modification_date": "2026-09-22T14:43:05", "link_label": "", "link_url": "", "canceled": "False", "cancel_reason": "", "place_and_room": "SV 1717", "url_place_and_room": "https://plan.epfl.ch/?room==SV%201717", "url_online_room": "https://epfl.zoom.us/j/68746410793", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "Invited Speaker and Student Speaker", "organizer": "Institute of Bioengineering", "contact": "<a href=\"mailto:[email protected]?subject=EPFL%20BioE%20Talks%20Series\">Fiorella Ghisays</a>, Institute of Bioengineering", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "", "file": "https://memento.epfl.ch/public/upload/files/BioEngineeringTalkMemento_u0lzmcg.jpg", "icalendar_url": "https://memento.epfl.ch/event/export/121879/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/1/?format=api", "https://memento.epfl.ch/api/v1/mementos/5/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api", "https://memento.epfl.ch/api/v1/mementos/8/?format=api", "https://memento.epfl.ch/api/v1/mementos/9/?format=api", "https://memento.epfl.ch/api/v1/mementos/111/?format=api", "https://memento.epfl.ch/api/v1/mementos/434/?format=api" ] }, { "id": 72460, "title": "MechE Colloquium: Local Rheological Probes of Stress Heterogeneities in Active and Passive Fluids", "slug": "meche-colloquium-local-rheological-probes-of-stres", "event_url": "https://memento.epfl.ch/event/meche-colloquium-local-rheological-probes-of-stres", "visual_url": "https://memento.epfl.ch/image/33708/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33708/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33708/max-size.jpg", "lang": "en", "start_date": "2026-10-27", "end_date": "2026-10-27", "start_time": "12:00:00", "end_time": "13:00:00", "description": "<strong>Abstract: </strong>In this talk I will discuss our recent results on the microscopic physical origins of shear thickening in two vastly different materials: colloidal suspensions and active gels. In the first part of my talk, I will introduce a method we have developed that allows us to resolve the spatial distribution of stresses in sheared soft-materials, known as Boundary Stress Microscopy. We have applied this technique to suspensions undergoing shear thickening. I will present our results on the existence of clearly defined dynamically localized regions of substantially increased stress that appear intermittently at stresses well above the applied stress. Surprisingly, we find that these spatially distinct and dynamic phases quantitatively account for the observed shear thickening seen in sheared colloidal dispersions (e.g. Oobleck). In the second part of my talk I will discuss our results on the rheology of active matter. Our system is composed of microtubules and kinesin motor proteins that self-assemble to form complexes that propel themselves through the fluid. What results is a dramatic alteration in the measured viscosity. I will provide a simple physical model that fits the rheological response with zero fitting parameters. <br>\r\n<br>\r\n<strong>Biography: </strong>Daniel Blair is a Professor of physics and a co-founding member of the Institute for Soft Matter Synthesis and Metrology I(SM)2 at Georgetown University. Prior to joining Georgetown in 2007, Professor Blair was a postdoctoral fellow at Harvard University in the Paulson School of Engineering and the Department of Physics. In 2009, he was awarded the NSF Career Award and has done pioneering work into the structure and rheology of soft and biological materials. His group has developed a variety of tools and techniques centered on quantitative 4D microscopy coupled with microfluidic and rheometric methods. ", "image_description": "Prof. Daniel Blair", "creation_date": "2026-08-27T16:32:32", "last_modification_date": "2026-09-29T12:28:07", "link_label": "Prof. Sangwoo Kim - MESOBIO", "link_url": "https://www.epfl.ch/labs/mesobio/", "canceled": "False", "cancel_reason": "", "place_and_room": "MED 0 1418", "url_place_and_room": "https://plan.epfl.ch/?room==MED%200%201418", "url_online_room": "https://epfl.zoom.us/j/61360740951", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "<a href=\"https://physics.georgetown.edu/daniel-blair/\">Prof. Daniel Blair</a>, <a href=\"https://physics.georgetown.edu/\">Department of Physics</a>, <a href=\"https://www.georgetown.edu/\">University of Georgetown</a>, USA", "organizer": "<a href=\"mailto:[email protected]?subject=MechE%20Colloquium%20-%20Daniel%20Blair\">MechE Colloquium</a>", "contact": "<a href=\"mailto:[email protected]?subject=MechE%20Colloquium%20-%20Daniel%20Blair\">Prof. Sangwoo Kim</a>", "is_internal": "False", "theme": "", "vulgarization": { "id": 1, "fr_label": "Tout public", "en_label": "General public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "MechE Colloquium: Local Rheological Probes of Stress Heterogeneities in Active and Passive Fluids", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/121614/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/1/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api", "https://memento.epfl.ch/api/v1/mementos/8/?format=api", "https://memento.epfl.ch/api/v1/mementos/111/?format=api", "https://memento.epfl.ch/api/v1/mementos/232/?format=api", "https://memento.epfl.ch/api/v1/mementos/270/?format=api" ] }, { "id": 71376, "title": "EPFL Latsis Symposium 2026: “Decoding the Cell: Modeling, Predicting, and Engineering Cellular States”", "slug": "epfl-latsis-symposium-2026-decoding-the-cell-model", "event_url": "https://memento.epfl.ch/event/epfl-latsis-symposium-2026-decoding-the-cell-model", "visual_url": "https://memento.epfl.ch/image/32724/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/32724/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/32724/max-size.jpg", "lang": "en", "start_date": "2026-10-29", "end_date": "2026-10-30", "start_time": null, "end_time": null, "description": "<div class=\"ms-outlook-mobile-reference-message skipProofing\">The <strong>EPFL Latsis Symposium 2026<em>: “Decoding the Cell: Modeling, Predicting, and Engineering Cellular States”</em></strong> will be held on <strong>October 29-30, 2026</strong>, at the <strong>Olympic Museum in Lausanne</strong>.<br>\r\n<br>\r\nThis international gathering will bring together leading scientists in single-cell analysis, computational modeling, and cellular engineering to explore how recent breakthroughs in multi-omics technologies, predictive algorithms, and synthetic biology are reshaping our understanding of cellular function.<br>\r\n<br>\r\nThrough interdisciplinary talks and discussions, the symposium will spotlight advances in single-cell multi-modal data integration, predictive modeling of cell identity and behavior, and the engineering of synthetic cell states. By connecting researchers across experimental and computational domains, the event aims to establish new conceptual and technological frameworks for modeling and controlling cellular systems.<br>\r\n<br>\r\nHosted by EPFL, the symposium will foster scientific exchange, spark new collaborations, and accelerate progress toward next-generation cell-based therapies, disease models, and synthetic biological innovations.<br>\r\n<br>\r\nJoin us in Lausanne to connect with the global community shaping the future of cell understanding and engineering.<br>\r\n<br>\r\n<strong><a href=\"https://latsis2026.epfl.ch/event/1/\">Abstract submission deadline: September 15, 2026</a><br>\r\n<a href=\"https://latsis2026.epfl.ch/event/1/\">Registration deadline: September 30, 2026</a></strong><br>\r\n<br>\r\n<strong>CALL FOR ABSTRACTS IS OPEN</strong><br>\r\nA few reasons it is worth submitting an abstract:</div>\r\n\r\n<div>\r\n<ul>\r\n\t<li>Direct, in-depth conversations with attendees and our invited speakers</li>\r\n\t<li>A chance to network and spark new collaborations</li>\r\n\t<li>Ideal for sharing ongoing or preliminary results and getting early feedback</li>\r\n\t<li>Possibility to be selected for an abstract talk</li>\r\n\t<li>Eligible for our Best Poster Prize worth CHF 500, voted by symposium participants</li>\r\n</ul>\r\n</div>\r\n<strong>WHY ATTEND</strong>\r\n\r\n<ul>\r\n\t<li> World-class science - 11 invited experts, including speakers from Stanford, Cambridge, the Wellcome Sanger Institute, ETH Zurich, the Allen Institute, and other leading institutions</li>\r\n\t<li> Intimate format - a curated, discussion-driven programme with direct access to speakers</li>\r\n\t<li> Cross-disciplinary by design - connecting computational, experimental, and engineering approaches to cellular states</li>\r\n\t<li> Best poster prize - voted by participants</li>\r\n\t<li> A full conference experience - coffee breaks, lunches, dinner on Day 1, and complimentary access to the museum's exhibition at the close of the symposium</li>\r\n</ul>\r\n<strong>VENUE</strong><br>\r\nThe Olympic Museum is perched on the shores of Lake Geneva, with panoramic views of the Alps. It offers an exceptional setting for scientific exchange and networking.<br>\r\n<br>\r\n<strong>CONFIRMED SPEAKERS INCLUDE</strong>\r\n\r\n<ul>\r\n\t<li> <strong>Gray Camp </strong>- Roche Institute for Translational Bioengineering, Basel</li>\r\n\t<li> <strong> Barbara Engelhardt </strong>- Stanford University</li>\r\n\t<li> <strong>Jeremy Gunawardena</strong> - Pompeu Fabra University</li>\r\n\t<li> <strong>Muzlifah Haniffa </strong>- Wellcome Sanger Institute & University of Cambridge</li>\r\n\t<li><strong> Prisca Liberali</strong> - ETH Zurich & Friedrich Miescher Institute for Biomedical Research</li>\r\n\t<li> <strong> Steve Quake </strong>- Stanford University</li>\r\n\t<li> <strong>Susanne Rafelski</strong> - Allen Institute for Cell Science</li>\r\n\t<li> <strong> Kevin Tsia </strong>- University of Hong Kong</li>\r\n\t<li> <strong>Bo Wang </strong>- University Health Network & University of Toronto</li>\r\n</ul>\r\n<br>\r\n<em>We gratefully acknowledge the support of the Latsis International Foundation, Alithea Genomics, Cytosurge, 10x Genomics, and Stemcell Technologies, whose contributions help make this symposium possible.</em>", "image_description": "In a galaxy not so far, far away… Jakob J. Langer, Postdoctoral researcher, Lutolf Lab.", "creation_date": "2026-03-13T14:52:09", "last_modification_date": "2026-09-07T13:25:04", "link_label": "Registration & abstract submission", "link_url": "https://latsis2026.epfl.ch/event/1/", "canceled": "False", "cancel_reason": "", "place_and_room": "Olympic Museum", "url_place_and_room": "", "url_online_room": "", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "<a href=\"https://www.epfl.ch/labs/deplanckelab/latsis-symposium-2026/epfl-latsis-symposium-2026-invited-speakers/\">SPEAKERS</a>", "organizer": "LATSIS Symposium 2026 Organizing Committee:<br>\r\nProf. Bart Deplancke, Prof. Maria Brbić and Prof. Giovanni D’Angelo", "contact": "<a href=\"mailto:[email protected]\">[email protected]</a>", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 1, "fr_label": "Sur inscription", "en_label": "Registration required" }, "keywords": "", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/120078/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/8/?format=api", "https://memento.epfl.ch/api/v1/mementos/1/?format=api", "https://memento.epfl.ch/api/v1/mementos/111/?format=api", "https://memento.epfl.ch/api/v1/mementos/9/?format=api", "https://memento.epfl.ch/api/v1/mementos/416/?format=api", "https://memento.epfl.ch/api/v1/mementos/5/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api", "https://memento.epfl.ch/api/v1/mementos/27/?format=api" ] }, { "id": 72772, "title": "EPFL BioEngineering Talks", "slug": "epfl-bioengineering-talks-12", "event_url": "https://memento.epfl.ch/event/epfl-bioengineering-talks-12", "visual_url": "https://memento.epfl.ch/image/33988/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33988/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33988/max-size.jpg", "lang": "en", "start_date": "2026-11-02", "end_date": "2026-11-02", "start_time": "12:15:00", "end_time": "13:45:00", "description": "<p>Weekly BioEngineering Talks (Lunch Provided)<br>\r\n<br>\r\n<strong>INVITED SPEAKER:</strong><br>\r\n<strong>From single-molecule biophysics with Graphene Energy Transfer to Brownian DNA computing</strong><br>\r\n<strong><a href=\"https://tinnefeld.cup.uni-muenchen.de/publications/group-theses/https-tinnefeld-cup-uni-muenchen-de-members/philip-tinnefeld/\">Prof. Dr. Philip Tinnefeld</a>,</strong> LMU Munich<br>\r\nHost: <a href=\"https://people.epfl.ch/aleksandra.radenovic?lang=en\">Prof. Aleksandra Radenovic</a><br>\r\n<br>\r\n<u><strong>Abstract:</strong></u><br>\r\nGraphene-on-glass coverslips are an emerging microscopy platform as resonant energy transfer to graphene offers an axial ruler in the 5-40 nm range. I present single molecule biophysics experiments of protein/DNA interactions using Graphene Energy Transfer (GET) in combination with the discovery that dsDNA adopts a vertical orientation on graphene. Axial information of DNA structure and protein positions is deduced from GET-efficiency and xy-information is obtained e.g. by photon-efficient pMINFLUX revealing simultaneous bending and torsion of enzyme induced DNA conformations. Finally, I discuss how multi-color smFRET with dark quenchers probes states of DNA nanorobots and Brownian DNA computers that work close to the thermodynamic optimum.<br>\r\n<br>\r\n<u><strong>Bio:</strong></u><br>\r\nPhilip Tinnefeld is a Professor of Physical Chemistry at Ludwig-Maximilians-Universität München, leading a highly interdisciplinary NanoBioSciences research group that brings together molecular biology, biophysics, nanophotonics, and physical chemistry. He specialises in single-molecule detection and super-resolution microscopy, and he uses DNA origami to build modular nanoscale devices—such as force sensors, fluorescence amplifiers, and molecular robots—that can sense, compute, and respond autonomously. Under his leadership, the lab is also developing advanced biosensing platforms and imaging tools by combining DNA nanotechnology with 2D materials like graphene, pushing the frontiers of how we observe and control biological processes at the molecular level.<br>\r\n<br>\r\n<strong>STUDENT SPEAKER:</strong><br>\r\n<br>\r\n<strong>Understanding oxidative stress response in animals - a case study of the essential enzyme adenosylhomocysteinase, AHCY</strong><br>\r\n<strong><a href=\"https://people.epfl.ch/yong-qi.gao?lang=en\">Yong-Qi Gao</a>, </strong><a href=\"https://www.epfl.ch/labs/upzenk/\">Zenk Lab</a><br>\r\n<br>\r\n<br>\r\n------------------------------------------------------------------------------<br>\r\n<br>\r\n<strong>BioEngineering Talks mandatory EDBB Seminar Attendance (1st-Year PhD Students)</strong>\r\n</p><ul>\r\n\t<li> Attendance sheet to print <a class=\"text-link\" href=\"https://docs.google.com/document/d/1kusGxCFPAvWaRD8eUGEBkSVzD1ppMf1g/edit\" target=\"_blank\">HERE </a></li>\r\n</ul>\r\n<strong>The BioEngineering Student Seminar Series</strong> is an official course for which students can register and earn credits.<br>\r\n \r\n<ul>\r\n\t<li>Register <a class=\"text-link\" href=\"https://edu.epfl.ch/studyplan/fr/ecole_doctorale/biotechnologie-et-genie-biologique/coursebook/bioengineering-student-seminar-series-BIOENG-613\" target=\"_blank\">HERE</a></li>\r\n\t<li>Attendance sheet to print <a class=\"text-link\" href=\"https://docs.google.com/document/d/1ZGrPnt8LlLuWOApzx32s6L5UPPH8Hyoo/edit\" target=\"_blank\">HERE</a></li>\r\n</ul>\r\n<strong>General information:</strong><br>\r\nIn-person attendance is preferred to support your fellow students. Zoom is mainly for students on remote campuses; please notify <a class=\"text-link\" href=\"mailto:[email protected]\" target=\"_blank\">Fiorella Ghisays</a> in advance and join using your full name.<br>\r\nIf attending in person, have your sheet signed after the talk and keep the original, as no copy is retained.<br>\r\n ", "image_description": "", "creation_date": "2026-10-06T10:24:19", "last_modification_date": "2026-10-06T10:33:07", "link_label": "", "link_url": "", "canceled": "False", "cancel_reason": "", "place_and_room": "SV 1717", "url_place_and_room": "https://plan.epfl.ch/?room==SV%201717", "url_online_room": "https://epfl.zoom.us/j/68746410793", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "Invited Speaker and Student Speaker", "organizer": "Institute of Bioengineering", "contact": "<a href=\"mailto:[email protected]?subject=EPFL%20BioE%20Talks%20Series\">Fiorella Ghisays</a>, Institute of Bioengineering", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "", "file": "https://memento.epfl.ch/public/upload/files/BioEngineeringTalkMemento_u0lzmcg.jpg", "icalendar_url": "https://memento.epfl.ch/event/export/122074/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/5/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api", "https://memento.epfl.ch/api/v1/mementos/8/?format=api", "https://memento.epfl.ch/api/v1/mementos/9/?format=api", "https://memento.epfl.ch/api/v1/mementos/111/?format=api", "https://memento.epfl.ch/api/v1/mementos/434/?format=api" ] }, { "id": 72620, "title": "Inaugural Lectures SV - Paloma Navarro, Florian Schüder", "slug": "inaugural-lectures-sv-paloma-navarro-florian-schud", "event_url": "https://memento.epfl.ch/event/inaugural-lectures-sv-paloma-navarro-florian-schud", "visual_url": "https://memento.epfl.ch/image/33866/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33866/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33866/max-size.jpg", "lang": "en", "start_date": "2026-11-11", "end_date": "2026-11-11", "start_time": "17:15:00", "end_time": "19:30:00", "description": "<strong>Date</strong>: Wednesday November 11, 2026<br>\r\n<strong>Program: </strong>\r\n<ul>\r\n\t<li>17:15 - 17:25 Introduction by the Dean and Director GHI</li>\r\n\t<li>17:25 - 17:55 Prof. Paloma Navarro</li>\r\n\t<li>18:00 - 18:10 Introduction by the Dean and Director IBI</li>\r\n\t<li>18:10 - 18:40 Prof. Florian Schüder</li>\r\n\t<li>18:40 - 18:45 Closure</li>\r\n\t<li>18:45 Apéritif in SV Hall</li>\r\n</ul>\r\n<strong>Location: </strong><a href=\"https://plan.epfl.ch/?room==SV%201717\">SV1717</a><br>\r\n<strong>Registration: </strong><a href=\"https://docs.google.com/forms/d/19YVR2xdBv4gBMi4XxhpOA5un_tXsvrm9NLebElAFQZc/edit\">Click here</a><br>\r\n<br>\r\n============================================<br>\r\n<strong>Prof. Paloma Navarro</strong><br>\r\n<br>\r\n<strong>Engineering Precision Immunotherapies for the Aging Brain</strong><br>\r\n<br>\r\n<strong>Abstract</strong><br>\r\nAs we age, our brains slowly change memory can falter, thinking can slow, and the risk of diseases like Alzheimer's rises. For decades, aging research has focused on the brain's own cells. But our bodies also carry a second, powerful system that changes with age: the immune system. Best known for fighting infections, the immune system also reaches into the brain and helps shape how it works. My research aims to answer a simple but underexplored question: as the immune system ages, does it stop protecting the brain and start harming it, and if so, can we intervene?<br>\r\n<br>\r\nI will share how I have used engineered proteins, delivered directly into the brain, to precisely target specific immune cells and rebalance their behavior. Building on this work, my lab is now developing a toolkit of precision tools, each aimed at a different brain immune cell type. The goal is to translate this work into \"aging immunotherapies\": treatments that restore balance to the aging immune system, strengthen the brain's resilience, and reduce the risk of neurodegenerative disease.<br>\r\n<br>\r\n<strong>About the speaker</strong><br>\r\nPaloma Navarro Negredo studied Natural Sciences with an emphasis in Pharmacology at St John's College, University of Cambridge, before earning her Master's and PhD in Clinical Biochemistry, also at Cambridge. In the laboratory of Prof. Margaret S. Robinson she studied how proteins are sorted and trafficked inside cells. She then moved to Stanford University for postdoctoral research in the laboratory of Prof. Anne Brunet, supported by a Human Frontier Science Program fellowship. At Stanford she investigated changes in the aging brain, with a particular focus on immune cells and strategies to target them using engineered proteins.<br>\r\nPaloma is now an Assistant Professor at the School of Life Sciences at EPFL, where she leads a research group investigating how the aging immune system contributes to the decline of brain function.<br>\r\n<br>\r\n============================================<br>\r\n<strong>Prof. Florian Schüder</strong><br>\r\n<br>\r\n<strong>Programming DNA for Multiplexed Super-Resolution Microscopy</strong><br>\r\n<br>\r\n<strong>Abstract</strong><br>\r\nFluorescence microscopy is one of the most widely used tools in biological research, allowing us to visualize the organization of cells and their molecular components. Over the past two decades, the development of super-resolution microscopy has revolutionized the field by making it possible to visualize structures far smaller than previously thought possible with light microscopy.<br>\r\nMy research combines these advanced imaging techniques with tools from DNA nanotechnology to further expand what we can see and measure inside cells. In this presentation, I will introduce recent developments in DNA-based super-resolution microscopy and show how these approaches can enable high-resolution imaging of many different molecular targets within the same sample, and discuss how these technologies can be used to address biological questions at the molecular scale.<br>\r\n<br>\r\n<strong>About the speaker</strong><br>\r\nFlorian Schueder studied Physics at Ludwig Maximilian University of Munich and the Wyss Institute at Harvard University from 2009 to 2015. He then pursued a Ph.D. in Biophysics at the Max Planck Institute of Biochemistry from 2015 to 2020. From 2021 to 2025, he was a Postdoctoral Fellow in the Department of Cell Biology and the Department of Microbial Pathogenesis at Yale School of Medicine. In 2025, he was a Visiting Scientist at ETH Zurich. In 2026, Florian started his own lab as an Assistant Professor in the School of Life Sciences at EPFL.", "image_description": "", "creation_date": "2026-09-18T11:27:16", "last_modification_date": "2026-09-23T15:49:52", "link_label": "", "link_url": "", "canceled": "False", "cancel_reason": "", "place_and_room": "SV 1717", "url_place_and_room": "https://plan.epfl.ch/?room==SV%201717", "url_online_room": "", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "Prof. Paloma Navarro<br>\r\nProf. Florian Schüder", "organizer": "SV-DO", "contact": "[email protected]", "is_internal": "False", "theme": "", "vulgarization": { "id": 1, "fr_label": "Tout public", "en_label": "General public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/121860/", "category": { "id": 8, "code": "LI", "fr_label": "Leçons inaugurales - Leçons d'honneur", "en_label": "Inaugural lectures - Honorary Lecture", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/6/?format=api", "https://memento.epfl.ch/api/v1/mementos/8/?format=api", "https://memento.epfl.ch/api/v1/mementos/9/?format=api", "https://memento.epfl.ch/api/v1/mementos/111/?format=api" ] } ] }
