Neuromodulation of Neural Microcircuits NM² conference

The Blue Brain Project is delighted to announce that it will be hosting the second Neuromodulation of Neural Microcircuits NM² conference led by Srikanth Ramaswamy and Henry Markram. It will take place on May 24 – 26, in Champéry, Valais.

The overarching goal of the second NM² Conference is to provide a unifying and mechanistic view by which an ever-increasing number of neuromodulators, including monoamines, and peptides – the master switches – control genes, proteins, neurons and glia, dendrites, synapses, and emergent states in neural microcircuits across different brain regions in health and disease.
 
Building such a mechanistic view of neuromodulation encounters several fundamental challenges to consider:

1. How do sensory signals, internal brain states, and computations in microcircuits, trigger the release of specific neuromodulators?
2. How do neuronal assemblies and larger brain circuits respond to neuromodulators?
3. How do neuromodulators shape synaptic plasticity and brain states?