Synthetic tools for elucidation of the information layer beyond the genome sequence
Event details
| Date | 13.12.2016 |
| Hour | 17:15 › 18:30 |
| Speaker | Prof. Andreas Marx - University of Konstanz |
| Location | |
| Category | Conferences - Seminars |
In eukaryotes, proteins are often chemically modified during their “life span”. These posttranslational modifications represent an information level that is beyond the genetic code and varies with time and cellular location to allow cells to adjust protein activities to changes in intra- and extracellular conditions. Here, the protein-based modification ubiquitin and nucleic acid-reminiscent modification poly(ADP-ribose) are of particular interest for us. I will report on our recent results in studies of these biopolymers using synthetic tools. Recent studies have highlighted the paramount importance of “non-standard” Watson-Crick nucleobases in DNA and RNA. I will report on our recent results in the aim to develop simplified systems that allow tracing of these of these rare nucleobases.
Practical information
- General public
- Free
Organizer
- Prof. Fierz
Contact
- Marie Munoz