Evolution of the outer mitochondrial membrane
Event details
| Date | 05.12.2023 |
| Hour | 12:15 › 13:15 |
| Speaker | Lena Pernas, Dept. of Microbiology, Immunology and Molecular Genetics, UCLA, Los Angeles, USA / Metabolism of Infection Group, Max Planck Institute for Biology of Ageing, Cologne, Germany / HHMI Freeman Hrabowski Scholar |
| Location | |
| Category | Conferences - Seminars |
| Event Language | English |
The rewiring of mitochondrial metabolism serves as an innate immune-type defense mechanism that restricts the growth of the human parasite Toxoplasma gondii. We recently reported a previously undescribed structure we term SPOT (structure positive for outer mitochondrial membrane (OMM) that emerges from the OMM during infection. We propose that Toxoplasma hijacks the formation of SPOTs, a cellular response to OMM import stress, to promote its growth. Here, I discuss the fate and function of these peculiar structures.
Practical information
- Informed public
- Free
Organizer
- Andrea Ablasser