EPFL Latsis / Sinergia Symposium 2022. Advances in Imaging Pathological Protein Assemblies: From Molecules to Disease
Event details
| Date | 01.09.2022 › 02.09.2022 |
| Hour | 08:15 › 19:00 |
| Speaker | Speaker list |
| Location | Online |
| Category | Conferences - Seminars |
| Event Language | English |
About
More than a century since pathological protein aggregates were first identified in the brain of patients with neurodegenerative diseases (NDDs) and we still do not have effective therapies to treat or slow the progression of NDDs or diagnostics for early detection and monitoring disease progression.
Recent findings are challenging traditional views about the composition, ultrastructural properties, and heterogeneity of protein pathologies in the brain, their mechanisms of formation and their and how we investigate and model pathological aggregation processes associated with NDs in the laboratory today.
The primary objective of this symposium is to gather leading scientists from different disciplines to discuss and debate the latest findings, share the latest advances from their group, and brainstorm collectively about how to leverage and integrate the latest conceptual and technical advances in imaging and image analyses to address current knowledge and technological gaps and advance translational research in NDDs.
Sessions include:
September 1st
September 2nd
More than a century since pathological protein aggregates were first identified in the brain of patients with neurodegenerative diseases (NDDs) and we still do not have effective therapies to treat or slow the progression of NDDs or diagnostics for early detection and monitoring disease progression.
Recent findings are challenging traditional views about the composition, ultrastructural properties, and heterogeneity of protein pathologies in the brain, their mechanisms of formation and their and how we investigate and model pathological aggregation processes associated with NDs in the laboratory today.
The primary objective of this symposium is to gather leading scientists from different disciplines to discuss and debate the latest findings, share the latest advances from their group, and brainstorm collectively about how to leverage and integrate the latest conceptual and technical advances in imaging and image analyses to address current knowledge and technological gaps and advance translational research in NDDs.
Sessions include:
September 1st
- Opening session
- Plenary Lecture: Deconstructing and Reconstructing the Complexity of Proteinopathies
- Deconstructing and Reconstructing the Complexity of Proteinopathies
- The structural landscape of pathological aggregates
- New tools and approaches to capture the molecular diversity of pathological aggregates and elucidate their role in disease pathogenesis
- Panel discussions
- Poster sessions
- Dinner
September 2nd
- Plenary Lecture: Structure-based discovery of small-molecules that disassemble tau fibrils of Alzheimer's disease
- Progress towards developing PET imaging tracers
- Reverse Engineering the pathology of neurodegenerative diseases
- System-based approaches to deciphering the genetic, molecular, and structural determinants of pathology formation in neurodegenerative diseases
- Panel discussions
- Poster sessions
- Closing session
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